International open-label, uncontrolled, non-interventional, multi-centre observational program conducted by the HZRM, Frankfurt-Mörfelden, Germany

To be enrolled in the study, patients have to fulfill inclusion criteria

The ObsITI study is conducted by the experienced Haemophilia Center Rhine-Main (HZRM)

Scientists with international recognition evaluate and document data from patients on the success of ITI.

7 optional satellite studies will allow the investigators to correlate the individual success of ITI and to individualize the ITI treatment.